Rob Tarran, PhD - Scientific Founder & Chair, SAB

Rob is the scientific founder of Spyryx Biosciences and has been a board director since the Company was formed in 2013.  He is an Associate Professor in UNC-Chapel Hill's Department of Cell Biology and Physiology and a member of the Lineberger Cancer Center and the Cystic Fibrosis Center. He is also the Director of UNC’s NIH/FDA-funded Tobacco Center of Regulatory Science and Co-Director of UNC’s Cystic Fibrosis Program Project Grant.  Rob currently serves on multiple advisory and steering committees for the FDA and for the Cystic Fibrosis Foundation.   His research interests have centered around studying the role of ion channels in relation to the abnormal fluid hydration commonly seen in lung diseases such as CF, COPD, and asthma.  He trained at Newcastle University, UK where he performed CFTR electrophysiology and at UNC-Chapel Hill where he studied epithelial transport and CF pathogenesis.  Rob has published over 50 papers and it is his work on how defective CFTR function leads to dehydrated mucus and chronic lung disease that led to the discoveries upon which Spyryx was founded.  Another of Rob's contributions to the field includes the co-development of the confocal-based airway surface liquid (ASL) height assay that is now being widely adopted to study CF and COPD.